Maintaining a healthy lifestyle while taking a statin can improve the effectiveness of the drug. Grapefruit juice increases blood levels of atorvastatin, lovastatin, and simvastatin, which actually increases the effectiveness of these drugs, but may also increase the risk of side effects. The risk of muscle … Other potential side effects include: Myopathy. Common side effects of all statins. The side effects can range from being mild to severe, and here’s a look at some of the most common. Each … Based on your overall risk, your doctor may recommend you take statins to help lower your cholesterol by a certain amount. But some people have side effects. It's good, for instance, to have high levels of HDL ("good") cholesterol. At the same time, they lower triglycerides and raise HDL cholesterol levels. Talk to your doctor first to make sure the supplement won't interact with any of your other medications. Statin drugs work by blocking the action of the liver enzyme that is responsible for producing cholesterol. You may be more likely to have side effects if you:Â. Is High Cholesterol Putting Your Health at Risk? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. From there, it is eliminated from the body. Which Drugs Lower My Bad (LDL) Cholesterol? Can you drink alcohol while taking Livalo (pitavastatin)? Studies also show that statins can reduce the chances of recurrent strokes or heart attacks by about 40%. According to the American College of Cardiology, around 85–90% of people who take statins do not experience any side effects. The most commonly reported side effects of statins include: a headache; belching or excessive gas; constipation; croaky voice or hoarseness; difficulty sleeping; heartburn, indigestion, nausea, or stomach discomfort; lower back or side pain, tenderness around the eyes or cheekbones; nasal congestion or stuffiness, or a runny nose ; slight muscle pain; sweating. As … Get Tips to Avoid Health Problems, Slideshow: 16 Tips to Lower Cholesterol and Prevent Heart Disease, Slideshow: Cholesterol Too High? Drugs That May Help. Always consult with your physician or pharmacist before adjusting the dosage or taking any other medication, including over-the-counter or prescription drugs, herbal supplements, or vitamins. Side effects reported by some people include muscle pain and digestive problems. © 2005 - 2019 WebMD LLC. However, in most cases, experts consider the benefits outweigh the risks. Muscle pain is the most common side effect caused by statin use. The most commonly reported side effects of statins include: A headache; belching or excessive gas; constipation; croaky voice or hoarseness; difficulty sleeping; heartburn, indigestion, nausea, or stomach discomfort; lower back or side pain, tenderness around the eyes or cheekbones; nasal congestion or stuffiness, or a runny nose ; slight muscle pain; sweating. Weigh the risks and benefits. The most commonly reported side effects of statins include: Other side effects, such as liver damage, are rare, and it is not necessary to have ongoing liver tests while you are taking a statin once you have had a baseline liver function test completed. Most patients tolerate statins well, but like all medications, statins can cause side effects, which tend to be more severe as the statin dose and potency increase. These include: Muscle damage. The manufacturer’s advice is to avoid drinking grapefruit juice while taking statins. Estimates are that in addition to the people already taking them, another 15 million to 20 million people should be taking statin drugs based on their risk factors for heart disease. Numerous side effects are associated with statins and these side effects can often deter patients from using the drug. Talk to your doctor first to make sure the supplement won't interact with any of your other medications. How is Livalo (pitavastatin) different from other statins? heartburn, indigestion, nausea, or stomach discomfort, lower back or side pain, tenderness around the eyes or cheekbones, nasal congestion or stuffiness, or a runny nose, Excessive thirst or having to urinate frequently, Unexplained significant joint or muscle pain, tenderness, or weakness. ", Journal of Clinical Lipidology: “The risks of statin use in pregnancy: A systematic review.”, Mayo Clinic: “Statin Side Effects: Weigh the Benefits and Risks.”. Some patients decide to stop taking statins, a cholesterol-lowering drug, if they experience side effects. Some things can increase your risk of side effects with statins. It’s not uncommon for us to feel aches and pains in our muscles. All rights reserved. WebMD does not provide medical advice, diagnosis or treatment. In … Some of the more common statin side effects include headache and gastrointestinal symptoms. Is Repatha (evolocumab) effective without a statin? Sudden blood clots in these narrowed arteries can cause a heart attack or stroke. Some studies link statin use with birth defects. In Summary. Dr. Beatrice Golomb of San Diego, California is currently conducting a series of studies on statin side effects. Statins can cause muscle pains, especially in high doses. We comply with the HONcode standard for trustworthy health information -. A new study tracked how they did. Studies show that, in certain people, statins reduce the risk of heart attack, stroke, and even death from heart disease by about 25% to 35%. Statins do cause muscle pain, although the reported prevalence varies from 0.3 to 33% depending on the source. The most common side effect is muscle pain and weakness, a condition called rhabdomyolysis, most likely due to the depletion of Co-Q 10, a nutrient that supports muscle function. Statins lower LDL cholesterol and total cholesterol levels. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Some large studies have shown no effect, and have implied that statins pose no threat and may, in fact, prevent dementia, whereas others found an association between statin use and memory loss and confusion, prompting the FDA to order labeling changes on all statins. Last updated on Sep 1, 2020. Coenzyme Q10 supplements may help prevent statin side effects in some people, though more studies are needed to determine any benefits of taking it. Medical professionals estimate the true occurrence of muscle pain is approximately 50-100 out of 10,000 (0.5-1%) people treated over five years. People who drink large amounts of alcohol or who take other medicines that may interact are also at a higher risk. Weigh the risks and benefits. That buildup can eventually cause the arteries to narrow or harden. Statins are linked to a few rare but potentially serious side effects, including: Myositis, which is inflammation of the muscles. The most common statin side effects include: Less common side effects you may have with statins are: Statins also carry warnings that memory loss, mental confusion, neuropathy, high blood sugar, and type 2 diabetes are possible side effects. People who take a statin are more likely to develop diabetes than people who don’t. Sign Up to Receive Our Free Coroanvirus Newsletter, Alternative Treatments for High Cholesterol, Diabetes? Quiz: What You Need to Know About Cholesterol Medicines. Select one or more newsletters to continue. Too much cholesterol in the blood can cause a buildup of plaque on the walls of the arteries. It's important to remember that statins may also interact with other medications you take. Side effects. By lowering the levels, they help prevent heart attacks and stroke. It's possible that your blood sugar (blood glucose) level may slightly increase when you take a statin, which can lead to type 2 diabetes. However, statins can also cause more serious side effects. This variation may be due to the different ways muscle pain is described (such as muscle weakness, cramps, or muscle pain) and the fact patients are usually told to “Watch out for muscle problems!”, which tends to lead to an over-reporting of muscle complaints, commonly called the “nocebo” effect. ", American Academy of Family Physicians: "Cholesterol-Lowering Medications. ", FDA: "Important safety label changes to cholesterol-lowering statin drugs. Statins may also help to stabilize plaques in the arteries, making heart attacks less likely. Some foods and medications don’t mix well with statins and can make side effects worse: There are other medications that can cause problems if you take them with statins. HDL cholesterol prevents plaque buildup in the arteries by transporting the bad (LDL) cholesterol out of the blood to the liver.